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NKX2-1 抗体 (N-Term)

NKX2-1 适用: 人, 小鼠, 大鼠 WB, IF, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991652
发货至: 中国
  • 抗原 See all NKX2-1 抗体
    NKX2-1 (NK2 Homeobox 1 (NKX2-1))
    抗原表位
    • 14
    • 11
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 76
    • 36
    • 36
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 49
    • 28
    克隆类型
    • 41
    • 36
    多克隆
    标记
    • 36
    • 7
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NKX2-1 antibody is un-conjugated
    应用范围
    • 40
    • 36
    • 29
    • 25
    • 20
    • 13
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    NKX2-1 antibody is predicted to not cross-react with other NK2 homeobox family members. At least three isoforms of NKX2-1 are known to exist, this antibody will detect all three.
    纯化方法
    NKX2-1 Antibody is affinity chromatography purified via peptide column.
    免疫原
    NKX2-1 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NKX2-1. The immunogen is located within the first 50 amino acids of NKX2-1.
    亚型
    IgG
    Top Product
    Discover our top product NKX2-1 Primary Antibody
  • 应用备注
    NKX2-1 antibody can be used for detection of NKX2-1 by Western blot at 0.25 - 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    NKX2-1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    NKX2-1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    NKX2-1 (NK2 Homeobox 1 (NKX2-1))
    别名
    NKX2-1 (NKX2-1 产品)
    别名
    BCH antibody, BHC antibody, NK-2 antibody, NKX2.1 antibody, NKX2A antibody, TEBP antibody, TITF1 antibody, TTF-1 antibody, TTF1 antibody, titf1-A antibody, Xnkx-2.1 antibody, NKX2-1 antibody, LOC100227803 antibody, AV026640 antibody, Nkx2.1 antibody, T/EBP antibody, Titf1 antibody, Ttf-1 antibody, nk2.1a antibody, nkx2.1 antibody, nkx2.4a antibody, titf1 antibody, titf1a antibody, NK2 homeobox 1 antibody, NK2 homeobox 1 L homeolog antibody, NK2 homeobox 4b antibody, NKX2-1 antibody, nkx2-1.L antibody, Nkx2-1 antibody, nkx2.4b antibody
    背景
    NKX2-1 Antibody: NKX2-1 (NK2 homeobox 1) has been identified as a thyroid-specific transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin and thyrotropin receptor. NKX2-1 is crucial in the maintenance of the thyroid differentiation phenotype and morphogenesis. It contains one homeobox DNA-binding domain. NKX2-1 also may play a role in lung development and surfactant homeostasis. Mutations and deletions in this gene are associated with benign hereditary chorea, congenital hypothyroidism, neonatal respiratory distress, and may be associated with thyroid cancer. NKX2-1 has been suggested to be a candidate suppressor of malignant progression.
    分子量
    Predicted: 46 kDa

    Observed: 41, 45 kDa
    基因ID
    7080
    UniProt
    P43699
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
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