NKX2-1 抗体 (N-Term)
Quick Overview for NKX2-1 抗体 (N-Term) (ABIN6991652)
抗原
See all NKX2-1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- NKX2-1 antibody is predicted to not cross-react with other NK2 homeobox family members. At least three isoforms of NKX2-1 are known to exist, this antibody will detect all three.
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纯化方法
- NKX2-1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- NKX2-1 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NKX2-1. The immunogen is located within the first 50 amino acids of NKX2-1.
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亚型
- IgG
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anti-NK2 Homeobox 1 (NKX2-1) antibody
NKX2-1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-NK2 Homeobox 1 (NKX2-1) antibodyNKX2-1 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Monoclonal 6C11 unconjugated Recombinant Antibody
anti-NK2 Homeobox 1 (NKX2-1) antibodyNKX2-1 适用: 人, 小鼠, 大鼠 IHC, StM 宿主: 兔 Monoclonal NX2-1-1855R unconjugated Recombinant Antibody
anti-NK2 Homeobox 1 (NKX2-1) antibodyNKX2-1 适用: 人, 小鼠, 大鼠 IHC, StM 宿主: 小鼠 Monoclonal rNX2-1-690 unconjugated Recombinant Antibody
anti-NK2 Homeobox 1 (NKX2-1) antibodyNKX2-1 适用: 人, 小鼠, 大鼠 IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal 8G7G3-1 unconjugated
anti-NK2 Homeobox 1 (NKX2-1) antibodyNKX2-1 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-312R unconjugated Recombinant Antibody
anti-NK2 Homeobox 1 (NKX2-1) (AA 1-30), (N-Term) antibodyNKX2-1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB28559 unconjugated
anti-NK2 Homeobox 1 (NKX2-1) antibodyNKX2-1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-NK2 Homeobox 1 (NKX2-1) (AA 77-158) antibodyNKX2-1 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 2B9 unconjugated
anti-NK2 Homeobox 1 (NKX2-1) (N-Term) antibodyNKX2-1 适用: 人 IHC, IHC (p), HIER 宿主: 小鼠 Monoclonal SPT24 unconjugated
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应用备注
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NKX2-1 antibody can be used for detection of NKX2-1 by Western blot at 0.25 - 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- NKX2-1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- NKX2-1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- NKX2-1 (NK2 Homeobox 1 (NKX2-1))
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别名
- NKX2-1
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背景
- NKX2-1 Antibody: NKX2-1 (NK2 homeobox 1) has been identified as a thyroid-specific transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin and thyrotropin receptor. NKX2-1 is crucial in the maintenance of the thyroid differentiation phenotype and morphogenesis. It contains one homeobox DNA-binding domain. NKX2-1 also may play a role in lung development and surfactant homeostasis. Mutations and deletions in this gene are associated with benign hereditary chorea, congenital hypothyroidism, neonatal respiratory distress, and may be associated with thyroid cancer. NKX2-1 has been suggested to be a candidate suppressor of malignant progression.
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分子量
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Predicted: 46 kDa
Observed: 41, 45 kDa -
基因ID
- 7080
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UniProt
- P43699
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
抗原
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