PPHLN1 抗体 (AA 160-210)
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北京 101111
Quick Overview for PPHLN1 抗体 (AA 160-210) (ABIN6991643)
抗原
See all PPHLN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 160-210
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纯化方法
- Periphilin Antibody is affinity chromatography purified via peptide column.
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免疫原
- Periphilin antibody was raised against a 16 amino acid synthetic peptide near the center of human Periphilin. The immunogen is located within amino acids 160 - 210 of Periphilin.
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亚型
- IgG
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应用备注
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Periphilin antibody can be used for detection of Periphilin by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Periphilin Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Periphilin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- PPHLN1 (Periphilin 1 (PPHLN1))
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别名
- Periphilin
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背景
- Periphilin Antibody: Periphilin, known as PPHLN1 or gastric cancer antigen Ga50, plays a role in epithelial differentiation and contributes to epidermal integrity and barrier formation. It interacts with periplakin, a known precursor of the cornified cell envelope. Periphilin 1 is ubiquitously expressed and localizes to nucleus and cytoplasm. Existing as eight alternatively spliced isoforms, Periphilin is highly insoluble and contains a putative nuclear localization signal (NLS) within its N-terminal half, a prerequisite for the formation of insoluble complexes and a possible caspase recognition sequence and a potential nuclear export signal. Periphilin may play an important role in the nervous system.
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基因ID
- 51535
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NCBI登录号
- NP_958848
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UniProt
- Q8NEY8
抗原
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