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PPHLN1 抗体 (N-Term)

PPHLN1 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6259270
发货至: 中国
  • 抗原 See all PPHLN1 抗体
    PPHLN1 (Periphilin 1 (PPHLN1))
    抗原表位
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 27
    • 21
    • 16
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 25
    • 3
    克隆类型
    • 26
    • 2
    多克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPHLN1 antibody is un-conjugated
    应用范围
    • 28
    • 13
    • 13
    • 8
    • 6
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    PPHLN Antibody detects endogenous levels of total PPHLN.
    预测反应
    Pig,Sheep,Rabbit,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human PPHLN, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product PPHLN1 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    PPHLN1 (Periphilin 1 (PPHLN1))
    别名
    PPHLN1 (PPHLN1 产品)
    别名
    MGC75908 antibody, MGC81987 antibody, wu:fb83c09 antibody, zgc:158246 antibody, si:ch211-155a11.2 antibody, HSPC232 antibody, 1110063K05Rik antibody, 1600022A19Rik antibody, CR antibody, HSPC206 antibody, periphilin 1 antibody, periphilin 1 S homeolog antibody, PPHLN1 antibody, pphln1 antibody, pphln1.S antibody, Pphln1 antibody
    背景

    Description: Component of the HUSH complex, a multiprotein complex that mediates epigenetic repression. The HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3. In the HUSH complex, contributes to the maintenance of the complex at chromatin (PubMed:26022416). Acts as a transcriptional corepressor and regulates the cell cycle, probably via the HUSH complex (PubMed:15474462, PubMed:17963697). May be involved in epithelial differentiation by contributing to epidermal integrity and barrier formation (Probable).

    Gene: PPHLN1

    分子量
    53 kDa
    基因ID
    51535
    UniProt
    Q8NEY8
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