PRICKLE1 抗体 (C-Term)
-
- 抗原 See all PRICKLE1 抗体
- PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))
-
抗原表位
- C-Term
- 适用
- 人, 大鼠, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PRICKLE1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 特异性
- Multiple isoforms of PRICKLE1 are known to exist. PRICKLE1 antibody is predicted to not cross-react with other PRICKLE protein family members.
- 纯化方法
- PRICKLE1 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- PRICKLE1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human PRICKLE1. The immunogen is located within the last 50 amino acids of PRICKLE1.
- 亚型
- IgG
- Top Product
- Discover our top product PRICKLE1 Primary Antibody
-
anti-Prickle-Like Protein 1 (PRICKLE1) (AA 684-756) antibody
PRICKLE1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8G5 unconjugated
anti-Prickle-Like Protein 1 (PRICKLE1) (AA 684-756) antibodyPRICKLE1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Prickle-Like Protein 1 (PRICKLE1) antibodyPRICKLE1 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prickle-Like Protein 1 (PRICKLE1) (C-Term) antibodyPRICKLE1 适用: 人, 大鼠, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
PRICKLE1 antibody can be used for detection of PRICKLE1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PRICKLE1 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- PRICKLE1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
- 抗原
- PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))
- 别名
- PRICKLE1 (PRICKLE1 产品)
- 别名
- EPM1B antibody, RILP antibody, Rilp antibody, 1110058P22Rik antibody, AW215793 antibody, Prickle antibody, mpk1 antibody, XPk antibody, pk-B antibody, prickle antibody, prickle-B antibody, Prickle-b antibody, prickle planar cell polarity protein 1 antibody, prickle planar cell polarity protein 1 L homeolog antibody, prickle planar cell polarity protein 1 S homeolog antibody, PRICKLE1 antibody, Prickle1 antibody, prickle1.L antibody, prickle1.S antibody
- 背景
- PRICKLE1 Antibody: PRICKLE1, also known as RILP or EPM1B, is a Disheveled-associated protein that serves as a nuclear translocation receptor for REST/NRSF and REST4 (1, 2). It contains three N-terminal LIM domains and three C-terminal nuclear localization signals. It localizes to the cytoplasm, as well as to the nuclear membrane and expressed at higher levels in placenta. PRICKLE1 is a negative regulator of the Wnt / beta-catenin signaling pathway and is a putative tumor suppressor in human HCCs. Defects in the gene encoding PRICKLE1 are associated with autosomal recessive progressive myoclonic epilepsy.
- 分子量
-
Predicted: 46, 91 kDa
Observed: 52, 90 kDa - 基因ID
- 144165
- NCBI登录号
- NP_694571
- UniProt
- Q96MT3
- 途径
- WNT signaling, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development, Protein targeting to Nucleus
-
