Uroplakin 1B 抗体 (AA 110-160)
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Quick Overview for Uroplakin 1B 抗体 (AA 110-160) (ABIN6991587)
抗原
See all Uroplakin 1B (UPK1B) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 110-160
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特异性
- At least two isoforms of UPK1B are known to exist, this antibody will recognize both isoforms. UPK1B antibody is predicted to not cross-react with other tetraspanin protein family members.
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纯化方法
- UPK1B Antibody is affinity chromatography purified via peptide column.
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免疫原
- UPK1B antibody was raised against a 17 amino acid synthetic peptide near the center of human UPK1B. The immunogen is located within amino acids 110 - 160 of UPK1B.
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亚型
- IgG
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应用备注
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UPK1B antibody can be used for detection of UPK1B by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- UPK1B Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- UPK1B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Uroplakin 1B (UPK1B)
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别名
- UPK1B
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背景
- UPK1B Antibody: Uroplakin-1B (UPK1B) is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. UPK1B is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins and may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.
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分子量
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Predicted: 29 kDa
Observed: 30 kDa -
基因ID
- 7348
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NCBI登录号
- NP_008883
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UniProt
- O75841
抗原
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