EI24 抗体 (C-Term)
This anti-EI24 antibody is a 兔 多克隆 antibody detecting EI24 in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
Quick Overview for EI24 抗体 (C-Term) (ABIN6991581)
抗原
See all EI24 抗体
EI24
(Etoposide Induced 2.4 (EI24))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This EI24 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- C-Term
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特异性
- At least two isoforms of EI24 are known to exist, this antibody will only detect the larger isoform.
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纯化方法
- EI24 Antibody is affinity chromatography purified via peptide column.
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免疫原
- EI24 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human EI24. The immunogen is located within the last 50 amino acids of EI24.
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亚型
- IgG
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anti-Etoposide Induced 2.4 (EI24) (AA 27-61) antibody
EI24 适用: 小鼠 WB 宿主: 兔 Polyclonal RB54173 unconjugated
anti-Etoposide Induced 2.4 (EI24) (C-Term) antibodyEI24 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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EI24 antibody can be used for detection of EI24 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in rat samples and Immunohistochemistry in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- EI24 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- EI24 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- EI24 (Etoposide Induced 2.4 (EI24))
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别名
- EI24
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背景
- EI24 Antibody: The etoposide-induced 24 (EI24) protein is an immediate-early induction target of p53-mediated apoptosis and functions as a tumor suppressor. EI24 contains six transmembrane domains and is localized to the endoplasmic reticulum (ER). It binds to Bcl-2 and may contribute to apoptosis by modulating the activity and function of Bcl-2. EI24 is highly mutated in aggressive breast cancers and its loss in breast cancer tissue correlates with tumor invasiveness. Similar findings in invasive cervical carcinoma suggest that EI24 may be a promising therapeutic target in the treatment of invasive cancer.
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基因ID
- 9538
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NCBI登录号
- NP_004870
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UniProt
- O14681
抗原
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