EI24 抗体 (C-Term)
EI24
适用: 人, 小鼠, 大鼠
WB, IHC (p), EIA
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all EI24 抗体
- EI24 (Etoposide Induced 2.4 (EI24))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EI24 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 19 amino acid synthetic peptide near the carboxy terminus of Human EI24
- 亚型
- IgG
- Top Product
- Discover our top product EI24 Primary Antibody
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anti-Etoposide Induced 2.4 (EI24) (AA 27-61) antibody
EI24 适用: 小鼠 WB 宿主: 兔 Polyclonal RB54173 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- EI24 (Etoposide Induced 2.4 (EI24))
- 别名
- EI24 (EI24 产品)
- 别名
- EPG4 antibody, PIG8 antibody, TP53I8 antibody, AA536736 antibody, AI115355 antibody, EI24, autophagy associated transmembrane protein antibody, etoposide induced 2.4 mRNA antibody, EI24 antibody, Ei24 antibody
- 背景
- The etoposide-induced 24 (EI24) protein is an immediate-early induction target of p53-mediated apoptosis and functions as a tumor suppressor. EI24 contains six transmembrane domains and is localized to the endoplasmic reticulum (ER). It binds to Bcl-2 and may contribute to apoptosis by modulating the activity and function of Bcl-2. EI24 is highly mutated in aggressive breast cancers and its loss in breast cancer tissue correlates with tumor invasiveness. Similar findings in invasive cervical carcinoma suggest that EI24 may be a promising therapeutic target in the treatment of invasive cancer.Synonyms: Etoposide-induced protein 2.4 homolog, PIG8, p53-induced gene 8 protein
- 基因ID
- 9538
- NCBI登录号
- NP_004870
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