SIK2 抗体 (AA 270-320)
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北京 101111
Quick Overview for SIK2 抗体 (AA 270-320) (ABIN6991528)
抗原
See all SIK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 270-320
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特异性
- SIK2 antibody is predicted to not cross-react with other SIK protein family members.
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纯化方法
- SIK2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- SIK2 antibody was raised against a 16 amino acid synthetic peptide near the center of human SIK2. The immunogen is located within amino acids 270 - 320 of SIK2.
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亚型
- IgG
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anti-Salt-Inducible Kinase 2 (SIK2) (AA 467-576) antibody
SIK2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C6 unconjugated
anti-Salt-Inducible Kinase 2 (SIK2) (AA 100-150) antibodySIK2 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Salt-Inducible Kinase 2 (SIK2) (AA 467-576) antibodySIK2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H6 unconjugated
anti-Salt-Inducible Kinase 2 (SIK2) (AA 674-916) antibodySIK2 适用: 小鼠 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Salt-Inducible Kinase 2 (SIK2) (AA 827-926) antibodySIK2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Salt-Inducible Kinase 2 (SIK2) (AA 281-330) antibodySIK2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Salt-Inducible Kinase 2 (SIK2) (AA 655-925) antibodySIK2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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SIK2 antibody can be used for detection of SIK2 by Western blot at 1 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- SIK2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- SIK2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SIK2 (Salt-Inducible Kinase 2 (SIK2))
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别名
- SIK2
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背景
- SIK2 Antibody: Salt-inducible kinase 2 (SIK2), like its closely related homolog SIK1, belongs AMPK subfamily of the Ser/Thr protein kinase family and negatively regulates CRE-binding protein (CREB) activity by phosphorylating the CREB-specific coactivator transducer of regulated CREB activity (TORC). SIK2 is thought to be part of a signaling cascade that regulates the expression and activity of the insulin-induced genes PGC-1 alpha and UCP-1 in brown adipocytes, impairment of which has been implicated in obesity and insulin resistance in human and animal models. SIK2 has also been reported as a key regulator for neuronal survival after ischemia, suppressing CREB-mediated gene expression after oxygen-glucose deprivation.
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基因ID
- 23235
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UniProt
- Q9H0K1
抗原
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