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ROCK2 抗体 (AA 920-970)

The 兔 多克隆 anti-ROCK2 antibody is suitable to detect ROCK2 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IF 和 IHC (p).
产品编号 ABIN6991526
发货至: 中国
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Quick Overview for ROCK2 抗体 (AA 920-970) (ABIN6991526)

抗原

See all ROCK2 抗体
ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ROCK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 920-970

    特异性

    Three isoforms of ROCK2 are known to exist, this antibody recognizes all three isoforms. ROCK2 antibody is predicted to not cross-react with other ROCK protein family members.

    纯化方法

    ROCK2 Antibody is affinity chromatography purified via peptide column.

    免疫原

    ROCK2 antibody was raised against a 15 amino acid synthetic peptide near the center of human ROCK2. The immunogen is located within amino acids 920 - 970 of ROCK2.

    亚型

    IgG
  • 应用备注

    ROCK2 antibody can be used for detection of ROCK2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    ROCK2 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    ROCK2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

    别名

    ROCK2

    背景

    ROCK2 Antibody: ROCK2 is a member of the AGC serine/threonine protein kinase family that regulates the assembly of the actin cytoskeleton. ROCK2 contains a protein kinase domain, a coiled-coil region and a zinc finger region and appears to be present as a dimer. ROCK2, like its isozyme ROCK1, is a downstream target of the small G-protein Rho and plays a role in smooth muscle contraction, malignant cell transformation, tumor invasion and metastasis, and mediates the cellular morphological changes during apoptosis.

    分子量

    Predicted: 153 kDa

    Observed: 160 kDa

    基因ID

    9475

    NCBI登录号

    NP_004841

    UniProt

    O75116

    途径

    Microtubule Dynamics, WNT signaling, Tube Formation
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