LY9 抗体 (C-Term)
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北京 101111
Quick Overview for LY9 抗体 (C-Term) (ABIN6991512)
抗原
See all LY9 (CD229) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 520-570, C-Term
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特异性
- At least three isoforms of SLAMF3 are known to exist. SLAMF3 antibody is predicted to not cross-react with other SLAM protein family members.
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纯化方法
- SLAMF3 Antibody is affinity chromatography purified via peptide column.
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免疫原
- SLAMF3 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SLAMF3. The immunogen is located within amino acids 520 - 570 of SLAMF3.
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亚型
- IgG
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应用备注
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SLAMF3 antibody can be used for detection of SLAMF3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- SLAMF3 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- SLAMF3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- LY9 (CD229) (Lymphocyte Antigen 9 (CD229))
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别名
- SLAMF3
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背景
- SLAMF3 Antibody: The signaling lymphocyte-activation molecule family member 3 (SLAMF3), also known as LY9, is a cell surface receptor that is expressed on T and B lymphocytes and belongs to the CD150/SLAMF1 receptor family. SLAMF3 was identified through a yeast two-hybrid screening in which SLAMF3 bound to the X-linked lymphoproliferative disease gene product SAP, suggesting that in activated T cells, SLAMF3 signaling can be triggered SAP. Its expression on the cell surface appears to be regulated via its interaction with the clathrin-associated adaptor complex 2 (AP-2). Despite its similarity to SLAMF1 in structure and interactions with SAP, SLAMF3-deficient mice do not exhibit phenotypic characteristics associated with SLAMF1- and SAP-deficient mice, suggesting that SLAMF3 plays other roles in T cell activation.
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基因ID
- 4063
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NCBI登录号
- NP_1769
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UniProt
- Q9HBG7
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途径
- BCR Signaling
抗原
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