ZNF346 antibody is predicted to not cross-react with other ZNF family members. Three isoforms of ZNF346 are known to exist, this antibody will recognize the two longest isoforms
纯化方法
ZNF346 (CT) Antibody is affinity chromatography purified via peptide column.
免疫原
ZNF346 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human ZNF346. The immunogen is located within the last 50 amino acids of ZNF346.
ZNF346
适用: 大鼠
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 594
应用备注
ZNF346 antibody can be used for detection of ZNF346 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
ZNF346 (CT) Antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
ZNF346 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原
ZNF346
(Zinc Finger Protein 346 (ZNF346))
别名
ZNF346
背景
ZNF346 (CT) Antibody: ZNF346, also known as JAZ (just another zinc-finger protein), is a nucleolar, zinc finger protein which preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids with high affinity via C2H2 zinc fingers. ZNF346 contains four CH-type zinc finger motifs that are connected by long (28-38) amino acid linker sequences. ZNF346 is expressed in all tissues tested and localizes to the nucleus, primarily the nucleolus. ZNF346 is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism. ZNF346 interacts with ILF3 in an RNA-independent manner and may be involved in cell growth and survival.