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ESRP2 抗体 (C-Term)

This anti-ESRP2 antibody is a 兔 多克隆 antibody detecting ESRP2 in WB, ELISA, IF 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN6991491
发货至: 中国

Quick Overview for ESRP2 抗体 (C-Term) (ABIN6991491)

抗原

See all ESRP2 抗体
ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This ESRP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    特异性

    RBM35B antibody is predicted to not cross-react with other RBM35/ESRP family members. At least three isoforms of RBM35B are known to exist, this antibody will detect all three.

    纯化方法

    RBM35B Antibody is affinity chromatography purified via peptide column.

    免疫原

    RBM35B antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human RBM35B. The immunogen is located within the last 50 amino acids of RBM35B.

    亚型

    IgG
  • 应用备注

    RBM35B antibody can be used for detection of RBM35B by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    RBM35B Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    RBM35B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

    别名

    RBM35B

    背景

    RBM35B Antibody: RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing programme induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.

    基因ID

    80004

    NCBI登录号

    NP_079215

    UniProt

    Q9H6T0
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