TMEM59 抗体 (N-Term)
Quick Overview for TMEM59 抗体 (N-Term) (ABIN6991448)
抗原
See all TMEM59 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 80-130, N-Term
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纯化方法
- TMEM59 Antibody is affinity chromatography purified via peptide column.
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免疫原
- TMEM59 antibody was raised against a 16 amino acid synthetic peptide near amino terminus of human TMEM59. The immunogen is located within amino acids 80 - 130 of TMEM59.
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亚型
- IgG
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anti-Transmembrane Protein 59 (TMEM59) antibody
TMEM59 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 59 (TMEM59) (AA 59-201) antibodyTMEM59 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 59 (TMEM59) (AA 36-230) antibodyTMEM59 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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TMEM59 antibody can be used for detection of TMEM59 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TMEM59 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TMEM59 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TMEM59 (Transmembrane Protein 59 (TMEM59))
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别名
- TMEM59
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背景
- TMEM59 Antibody: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.
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基因ID
- 9528
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NCBI登录号
- NP_004863
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UniProt
- Q9BXS4
抗原
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