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EFCAB4B 抗体 (C-Term)

This anti-EFCAB4B antibody is a 兔 多克隆 antibody detecting EFCAB4B in WB, ELISA, IF 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN6991440
发货至: 中国

Quick Overview for EFCAB4B 抗体 (C-Term) (ABIN6991440)

抗原

See all EFCAB4B 抗体
EFCAB4B (EF-Hand Calcium Binding Domain 4B (EFCAB4B))

适用

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人, 小鼠

宿主

  • 16
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克隆类型

  • 18
多克隆

标记

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This EFCAB4B antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 8
    • 3
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    • 1
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    AA 640-690, C-Term

    纯化方法

    EFCAB4B Antibody is affinity chromatography purified via peptide column.

    免疫原

    EFCAB4B antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human EFCAB4B. The immunogen is located within amino acids 640 - 690 of EFCAB4B.

    亚型

    IgG
  • 应用备注

    EFCAB4B antibody can be used for detection of EFCAB4B by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    EFCAB4B Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    EFCAB4B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    EFCAB4B (EF-Hand Calcium Binding Domain 4B (EFCAB4B))

    别名

    EFCAB4B

    背景

    EFCAB4B Antibody: EFCAB4B, also known as Calcium release-activated calcium channel regulator 2A, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation. EFCAB4B acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration. A closely related protein, EFCAB4A, is likely to play a similar role as EFCAB4B, but the detailed function of EFCAB4A is still under investigation.

    基因ID

    84766

    NCBI登录号

    NP_001138430

    UniProt

    Q9BSW2
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