EFCAB4B 抗体 (C-Term)
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Quick Overview for EFCAB4B 抗体 (C-Term) (ABIN6991440)
抗原
See all EFCAB4B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 640-690, C-Term
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纯化方法
- EFCAB4B Antibody is affinity chromatography purified via peptide column.
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免疫原
- EFCAB4B antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human EFCAB4B. The immunogen is located within amino acids 640 - 690 of EFCAB4B.
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亚型
- IgG
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应用备注
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EFCAB4B antibody can be used for detection of EFCAB4B by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- EFCAB4B Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- EFCAB4B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- EFCAB4B (EF-Hand Calcium Binding Domain 4B (EFCAB4B))
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别名
- EFCAB4B
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背景
- EFCAB4B Antibody: EFCAB4B, also known as Calcium release-activated calcium channel regulator 2A, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation. EFCAB4B acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration. A closely related protein, EFCAB4A, is likely to play a similar role as EFCAB4B, but the detailed function of EFCAB4A is still under investigation.
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基因ID
- 84766
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NCBI登录号
- NP_001138430
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UniProt
- Q9BSW2
抗原
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