WDR35 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for WDR35 抗体 (N-Term) (ABIN6991385)
抗原
See all WDR35 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 60-110, N-Term
-
特异性
- WDR35 antibody is human specific.
-
纯化方法
- WDR35 Antibody is affinity chromatography purified via peptide column.
-
免疫原
- WDR35 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human WDR35. The immunogen is located within amino acids 60 - 110 of WDR35.
-
亚型
- IgG
-
-
-
-
应用备注
-
WDR35 antibody can be used for detection of WDR35 by immunohistochemistry at 5 μ,g/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- WDR35 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- WDR35 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- WDR35 (WD Repeat Domain 35 (WDR35))
-
别名
- WDR35
-
背景
- WDR35 Antibody: WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have a wide range of functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription. One such protein, WDR35, also known as CED2, has been shown to be mutated in patients with Sensenbrenner syndrome/cranioectodermal dysplasia (CED), an autosomal-recessive disease that is characterized by craniosynstosis and ectodermal and skeletal abnormalities. WDR35 localizes to cilia and dentrosomes during embryogenesis and human and mouse fibroblasts that lack this gene fail to produce cilia. Mutations in this gene can also cause short-rib polydactyly syndromes due to abnormal ciliogenesis.
-
基因ID
- 57539
-
NCBI登录号
- NP_001006658
-
UniProt
- Q9P2L0
-
途径
- Hedgehog Signaling
抗原
-