电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

ZEB2 抗体 (C-Term)

This anti-ZEB2 antibody is a 兔 多克隆 antibody detecting ZEB2 in WB, ELISA, ICC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991366
发货至: 中国

Quick Overview for ZEB2 抗体 (C-Term) (ABIN6991366)

抗原

See all ZEB2 抗体
ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

适用

  • 53
  • 24
  • 17
  • 9
  • 8
  • 8
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 52
  • 4
  • 1

克隆类型

  • 52
  • 5
多克隆

标记

  • 42
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ZEB2 antibody is un-conjugated

应用范围

  • 45
  • 26
  • 21
  • 14
  • 10
  • 9
  • 8
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

    • 9
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    ZEB2 antibody is predicted to not cross-react with ZEB1.

    纯化方法

    ZEB2 Antibody is affinity chromatography purified via peptide column.

    免疫原

    ZEB2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human ZEB2. The immunogen is located within the last 50 amino acids of ZEB2.

    亚型

    IgG
  • 应用备注

    ZEB2 antibody can be used for detection of ZEB2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    ZEB2 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    ZEB2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

    别名

    ZEB2

    背景

    ZEB2 Antibody: ZEB2, initially identified as Smad interacting-protein 1, is normally located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Like the homologous ZEB1, ZEB2 inhibits the transcription of the E-cadherin gene and induces epithelial-mesenchymal transition, a genetic program controlling cell migration during embryonic development and wound healing, in vitro. ZEB2 can also protect cells from DNA damage-induced apoptosis, suggesting that its expression may contribute to tumor progression. Recent evidence has shown that ZEB2 is often observed in the cytoplasm in numerous cancer tissues, indicating that its localization may be regulated in normal and tumor tissues. Mutations in this gene are also associated with Hirschsprung disease/Mowat-Wilson syndrome.

    分子量

    Predicted: 134 kDa

    Observed: 135 kDa

    基因ID

    9839

    UniProt

    O60315

    途径

    Tube Formation
You are here:
Chat with us!