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SIRT4 抗体 (N-Term)

This anti-SIRT4 antibody is a 小鸡 多克隆 antibody detecting SIRT4 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991345
发货至: 中国

Quick Overview for SIRT4 抗体 (N-Term) (ABIN6991345)

抗原

See all SIRT4 抗体
SIRT4 (Sirtuin 4 (SIRT4))

适用

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  • 37
  • 27
  • 5
  • 5
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  • 4
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  • 3
  • 2
  • 1
  • 1
  • 1
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人, 小鼠, 大鼠

宿主

  • 58
  • 9
  • 1
  • 1
小鸡

克隆类型

  • 62
  • 7
多克隆

标记

  • 37
  • 9
  • 2
  • 2
  • 1
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  • 1
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  • 1
  • 1
  • 1
  • 1
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  • 1
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  • 1
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This SIRT4 antibody is un-conjugated

应用范围

  • 57
  • 20
  • 20
  • 10
  • 8
  • 4
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 12
    • 8
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 80-130, N-Term

    纯化方法

    SIRT4 Antibody is affinity chromatography purified via peptide column.

    免疫原

    SIRT4 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human SIRT4. The immunogen is located within amino acids 80 - 130 of SIRT4.

    亚型

    IgY
  • 应用备注

    SIRT4 antibody can be used for detection of SIRT4 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human and mouse samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    SIRT4 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    SIRT4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    SIRT4 (Sirtuin 4 (SIRT4))

    别名

    SIRT4

    背景

    SIRT4 Antibody: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT4 localizes to mitochondria, inhibits glutamate dehydrogenase, and is thought to be involved in the regulation of insulin secretion.

    分子量

    Predicted: 37 kDa

    Observed: 40 kDa

    基因ID

    23409

    UniProt

    Q9Y6E7

    途径

    Negative Regulation of Hormone Secretion
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