NSMCE2 抗体 (C-Term)
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北京 101111
Quick Overview for NSMCE2 抗体 (C-Term) (ABIN6991340)
抗原
See all NSMCE2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 170-220, C-Term
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纯化方法
- MMS21 Antibody is affinity chromatography purified via peptide column.
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免疫原
- MMS21 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human MMS21. The immunogen is located within amino acids 170 - 220 of MMS21.
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亚型
- IgG
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应用备注
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MMS21 antibody can be used for detection of MMS21 by Western blot at 0.5 - 1 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- MMS21 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- MMS21 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))
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别名
- MMS21
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背景
- MMS21 Antibody: MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression, this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2.
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分子量
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Predicted: 27 kDa
Observed: 30 kDa -
基因ID
- 286053
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NCBI登录号
- NP_775956
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UniProt
- Q96MF7
抗原
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