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NSMCE2 抗体 (C-Term)

This anti-NSMCE2 antibody is a 兔 多克隆 antibody detecting NSMCE2 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991340
发货至: 中国

Quick Overview for NSMCE2 抗体 (C-Term) (ABIN6991340)

抗原

See all NSMCE2 抗体
NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))

适用

  • 26
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 22
  • 4

克隆类型

  • 24
  • 2
多克隆

标记

  • 16
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NSMCE2 antibody is un-conjugated

应用范围

  • 11
  • 6
  • 6
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 170-220, C-Term

    纯化方法

    MMS21 Antibody is affinity chromatography purified via peptide column.

    免疫原

    MMS21 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human MMS21. The immunogen is located within amino acids 170 - 220 of MMS21.

    亚型

    IgG
  • 应用备注

    MMS21 antibody can be used for detection of MMS21 by Western blot at 0.5 - 1 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    MMS21 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    MMS21 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))

    别名

    MMS21

    背景

    MMS21 Antibody: MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression, this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2.

    分子量

    Predicted: 27 kDa

    Observed: 30 kDa

    基因ID

    286053

    NCBI登录号

    NP_775956

    UniProt

    Q96MF7
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