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PIAS1 抗体 (C-Term)

PIAS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991332
发货至: 中国
  • 抗原 See all PIAS1 抗体
    PIAS1 (Protein Inhibitor of Activated STAT, 1 (PIAS1))
    抗原表位
    • 7
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    • 1
    C-Term
    适用
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    人, 小鼠, 大鼠
    宿主
    • 44
    • 4
    克隆类型
    • 41
    • 7
    多克隆
    标记
    • 31
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    This PIAS1 antibody is un-conjugated
    应用范围
    • 39
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    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    纯化方法
    PIAS1 Antibody is affinity chromatography purified via peptide column.
    免疫原
    PIAS1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human PIAS1. The immunogen is located within the last 50 amino acids of PIAS1.
    亚型
    IgG
    Top Product
    Discover our top product PIAS1 Primary Antibody
  • 应用备注
    PIAS1 antibody can be used for detection of PIAS1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PIAS1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    PIAS1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    PIAS1 (Protein Inhibitor of Activated STAT, 1 (PIAS1))
    别名
    PIAS1 (PIAS1 产品)
    背景
    PIAS1 Antibody: The PIAS proteins (protein inhibitor of activated STAT) play a crucial role as transcriptional coregulators in various cellular pathways, including the STAT, p53 and the steroid hormone signaling pathway. The PIAS protein family includes at least five evolutionarily conserved genes, including PIAS1. The major function of the PIAS proteins is the control of gene transcription and can also act as small ubiquitin-like-modifier (SUMO) E3 ligases. PIAS1 binds specifically to STAT1, inhibiting STAT1-mediated gene activation and also binds to the Gu/RNA helicase II enzyme, leading to the proteolytic cleavage of Gu/RH-II. PIAS1 is a potent co-activator for CP2c-mediated alpha-globin expression in erythroid cells.
    基因ID
    8554
    NCBI登录号
    NP_057250
    UniProt
    O75925
    途径
    JAK/STAT Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C
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