ANAPC5 抗体 (AA 480-530)
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北京 101111
Quick Overview for ANAPC5 抗体 (AA 480-530) (ABIN6991325)
抗原
See all ANAPC5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 480-530
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纯化方法
- APC5 Antibody is affinity chromatography purified via peptide column.
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免疫原
- APC5 antibody was raised against a 17 amino acid synthetic peptide near the center of human APC5. The immunogen is located within amino acids 480 - 530 of APC5.
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亚型
- IgG
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anti-Anaphase Promoting Complex Subunit 5 (ANAPC5) (AA 1-755) antibody
ANAPC5 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Anaphase Promoting Complex Subunit 5 (ANAPC5) (AA 1-250) antibodyANAPC5 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Anaphase Promoting Complex Subunit 5 (ANAPC5) (AA 1-250) antibodyANAPC5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Anaphase Promoting Complex Subunit 5 (ANAPC5) (Internal Region) antibodyANAPC5 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Anaphase Promoting Complex Subunit 5 (ANAPC5) (AA 2-232) antibodyANAPC5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Anaphase Promoting Complex Subunit 5 (ANAPC5) (AA 1-755) antibodyANAPC5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Anaphase Promoting Complex Subunit 5 (ANAPC5) (AA 156-185) antibodyANAPC5 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB24572 unconjugated
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应用备注
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APC5 antibody can be used for detection of APC5 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- APC5 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- APC5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))
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别名
- APC5
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背景
- APC5 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC5 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. While little is known of APC5, it is thought that APC5 associates with other APC/C components APC1, APC4, and CDC23 interdependently, such that loss of any one subunit reduces binding between the remaining three.
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基因ID
- 51433
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UniProt
- Q9UJX4
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途径
- M Phase
抗原
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