ANAPC4 抗体 (N-Term)
This anti-ANAPC4 antibody is a 兔 多克隆 antibody detecting ANAPC4 in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991324
发货至:
中国
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Quick Overview for ANAPC4 抗体 (N-Term) (ABIN6991324)
抗原
See all ANAPC4 抗体
ANAPC4
(Anaphase Promoting Complex Subunit 4 (ANAPC4))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This ANAPC4 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- AA 40-90, N-Term
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纯化方法
- APC4 Antibody is affinity chromatography purified via peptide column.
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免疫原
- APC4 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human APC4. The immunogen is located within amino acids 40 - 90 of APC4.
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亚型
- IgG
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anti-Anaphase Promoting Complex Subunit 4 (ANAPC4) (AA 1-808) antibody
ANAPC4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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APC4 antibody can be used for detection of APC4 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- APC4 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- APC4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ANAPC4 (Anaphase Promoting Complex Subunit 4 (ANAPC4))
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别名
- APC4
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背景
- APC4 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC4 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. While little is known of APC4, it is thought that APC4 associates with other APC/C components APC1, APC5, and CDC23 interdependently, such that loss of any one subunit reduces binding between the remaining three.
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基因ID
- 29945
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UniProt
- Q9UJX5
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途径
- M Phase
抗原
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