APC2 抗体 (AA 240-290)
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北京 101111
Quick Overview for APC2 抗体 (AA 240-290) (ABIN6991322)
抗原
See all APC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 240-290
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纯化方法
- APC2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- APC2 antibody was raised against an 18 amino acid synthetic peptide near the center of human APC2. The immunogen is located within amino acids 240 - 290 of APC2.
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亚型
- IgG
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anti-APC Regulator of WNT Signaling Pathway 2 (APC2) (AA 2041-2181) antibody
APC2 适用: 人 ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 3A2G2 unconjugated
anti-APC Regulator of WNT Signaling Pathway 2 (APC2) (AA 849-898) antibodyAPC2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-APC Regulator of WNT Signaling Pathway 2 (APC2) (AA 2011-2221) antibodyAPC2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-APC Regulator of WNT Signaling Pathway 2 (APC2) (AA 122-152) antibodyAPC2 适用: 人 WB 宿主: 兔 Polyclonal RB53935 unconjugated
anti-APC Regulator of WNT Signaling Pathway 2 (APC2) (Middle Region) antibodyAPC2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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APC2 antibody can be used for detection of APC2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- APC2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- APC2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))
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别名
- APC2
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背景
- APC2 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC2 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. Like APC11, APC2 contains cullin and RING finger domains that are thought to be important in regulating ubiquitination activity.
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基因ID
- 10297
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UniProt
- O95996
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途径
- WNT signaling
抗原
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