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DCLK1 抗体 (C-Term)

This anti-DCLK1 antibody is a 兔 多克隆 antibody detecting DCLK1 in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991287
发货至: 中国

Quick Overview for DCLK1 抗体 (C-Term) (ABIN6991287)

抗原

See all DCLK1 抗体
DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This DCLK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    纯化方法

    DCLK1 Antibody is affinity chromatography purified via peptide column.

    免疫原

    DCLK1 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human DCLK1. The immunogen is located within the last 50 amino acids of DCLK1.

    亚型

    IgG
  • 应用备注

    DCLK1 antibody can be used for detection of DCLK1 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human and rat samples, Immunohistochemistry in mouse and rat samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    DCLK1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    DCLK1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

    别名

    DCLK1

    背景

    DCLK1 Antibody: DCLK1 is one of three doublecortin-like kinases similar to the Ca2+/calmodulin-dependent protein kinase (CaMK) family. DCLK1 mRNA, like that of the homologous DCLK2 and DCLK3, is highly expressed in adult brain, but only DCLK1 and DCLK2 transcripts are present in human fetal brain and the developing mouse embryo, suggesting that DCLK1 and DCLK2 may play roles in cortical development. The DCLK proteins are homologous to Doublecortin (DCX), a gene that is mutated in X-linked human lissencephaly. In mouse models where the DCX gene has been disrupted, DCLK1 expression increases slightly and appears to compensate for the loss of DCX, as mice mutant for both DCX and DCLK1 show a severe phenotype including perinatal lethality, disorganized neocortical layering, and profound hippocampal cytoarchitectural disorganization. Unlike DCLK1, DCLK2 expression does not change in DCX-null mice.

    分子量

    Predicted: 90 kDa

    Observed: 85 kDa

    基因ID

    9201

    NCBI登录号

    NP_004725

    UniProt

    O15075
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