CALHM1 抗体 (N-Term)
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北京 101111
Quick Overview for CALHM1 抗体 (N-Term) (ABIN6991269)
抗原
See all CALHM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 60-110, N-Term
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纯化方法
- CALHM1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- CALHM1 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human CALHM1. The immunogen is located within amino acids 60 - 110 of CALHM1.
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亚型
- IgG
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anti-Calcium Homeostasis Modulator 1 (CALHM1) (N-Term) antibody
CALHM1 适用: 人, 大鼠, 小鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Calcium Homeostasis Modulator 1 (CALHM1) (AA 202-346) antibodyCALHM1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calcium Homeostasis Modulator 1 (CALHM1) (AA 202-346) antibodyCALHM1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calcium Homeostasis Modulator 1 (CALHM1) (AA 295-344) antibodyCALHM1 适用: 人, 大鼠, 小鼠, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Calcium Homeostasis Modulator 1 (CALHM1) (AA 252-265), (Intracellular) antibodyCALHM1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium Homeostasis Modulator 1 (CALHM1) (AA 252-265), (Intracellular) antibody (Atto 594)CALHM1 适用: 人 IHC, IF, IC 宿主: 兔 Polyclonal Atto 594
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应用备注
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CALHM1 antibody can be used for detection of CALHM1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CALHM1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CALHM1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- CALHM1 (Calcium Homeostasis Modulator 1 (CALHM1))
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别名
- CALHM1
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背景
- CALHM1 Antibody: Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by a massive loss of neurons in several brain regions and by the presence of senile plaques comprised of aggregated amyloid-beta (Abeta) peptides produced by the endoproteolysis of the amyloid precursor protein (APP). The calcium homeostasis modulator 1 (CALHM1) is a recently identified multipass transmembrane glycoprotein that controls cytosolic Ca2+ concentration and Abeta levels. While some studies suggest CALHM1 is significantly associated with risk of AD, other reports suggest there is no link. CALHM1 has been suggested to modulate the Ca2+-dependent proteolytic process of APP through controlling the level of cytosolic Ca2+.
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基因ID
- 255022
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NCBI登录号
- NP_001001412
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UniProt
- Q8IU99
抗原
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