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- 抗原 See all CALHM1 抗体
- CALHM1 (Calcium Homeostasis Modulator 1 (CALHM1))
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抗原表位
- AA 202-346
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CALHM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人, 小鼠
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Calcium homeostasis modulator protein 1 protein (202-346AA)
- 亚型
- IgG
- Top Product
- Discover our top product CALHM1 Primary Antibody
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anti-Calcium Homeostasis Modulator 1 (CALHM1) (N-Term) antibody
CALHM1 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Calcium Homeostasis Modulator 1 (CALHM1) (AA 202-346) antibodyCALHM1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calcium Homeostasis Modulator 1 (CALHM1) (AA 295-344) antibodyCALHM1 适用: 人, 大鼠, 小鼠, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Calcium Homeostasis Modulator 1 (CALHM1) (AA 252-265), (C-Term), (Intracellular) antibodyCALHM1 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium Homeostasis Modulator 1 (CALHM1) (AA 252-265), (C-Term), (Intracellular) antibody (Atto 594)CALHM1 适用: 人, 大鼠, 小鼠 IHC, IF, ICC 宿主: 兔 Polyclonal Atto 594
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- 应用备注
- Recommended dilution: WB:1:500-1:5000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CALHM1 (Calcium Homeostasis Modulator 1 (CALHM1))
- 别名
- CALHM1 (CALHM1 产品)
- 别名
- FAM26C antibody, Fam26c antibody, RGD1564891 antibody, EG546729 antibody, calcium homeostasis modulator 1 antibody, novel protein similar to vertebrate calcium homeostasis modulator protein family antibody, CALHM1 antibody, LOC557535 antibody, Calhm1 antibody
- 背景
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Background: Pore-forming subunit of a voltage-gated ion channel required for sensory perception of sweet, bitter and umami tastes. Specifically present in type II taste bud cells, where it plays a central role in sweet, bitter and umami taste perception by inducing ATP release from the cell, ATP acting as a neurotransmitter to activate afferent neural gustatory pathways. Acts both as a voltage-gated and calcium-activated ion channel: mediates neuronal excitability in response to changes in extracellular Ca2+ concentration. Has poor ion selectivity and forms a wide pore (around 14 Angstroms) that mediates permeation of Ca2+, Na+ and K+, as well as permeation of monovalent anions. Acts as an activator of the ERK1 and ERK2 cascade. Triggers endoplasmic reticulum stress by reducing the calcium content of the endoplasmic reticulum. May indirectly control amyloid precursor protein (APP) proteolysis and aggregated amyloid-beta (Abeta) peptides levels in a Ca2+ dependent manner.
Aliases: CAHM1_HUMAN antibody, Calcium homeostasis modulator 1 antibody, Calcium homeostasis modulator protein 1 antibody, CALHM1 antibody, FAM26C antibody, Family with sequence similarity 26, member C antibody, MGC39514 antibody, MGC39617 antibody, OTTHUMP00000020413 antibody, Protein FAM26C antibody
- UniProt
- Q8IU99
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