KCNK18 抗体 (AA 210-260)
Our Local Distributor
北京 101111
Quick Overview for KCNK18 抗体 (AA 210-260) (ABIN6991251)
抗原
See all KCNK18 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 210-260
-
纯化方法
- TRESK Antibody is affinity chromatography purified via peptide column.
-
免疫原
- TRESK antibody was raised against a 17 amino acid synthetic peptide from near the center of human TRESK. The immunogen is located within amino acids 210 - 260 of TRESK.
-
亚型
- IgG
-
-
-
-
应用备注
-
TRESK antibody can be used for detection of TRESK by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- TRESK Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- TRESK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))
-
别名
- TRESK
-
背景
- TRESK Antibody: TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.
-
基因ID
- 338567
-
NCBI登录号
- NP_862823
-
UniProt
- Q7Z418
抗原
-