PRDM16 抗体 (C-Term)
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- 抗原 See all PRDM16 抗体
- PRDM16 (PR Domain Containing 16 (PRDM16))
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抗原表位
- AA 1120-1170, C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRDM16 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- PRDM16 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- PRDM16 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human PRDM16. The immunogen is located within amino acids 1120 - 1170 of PRDM16.
- 亚型
- IgG
- Top Product
- Discover our top product PRDM16 Primary Antibody
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anti-PR Domain Containing 16 (PRDM16) (AA 771-804) antibody
PRDM16 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB49517 unconjugated
anti-PR Domain Containing 16 (PRDM16) (AA 448-683) antibodyPRDM16 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 16 (PRDM16) (C-Term) antibodyVerified PRDM16 适用: 人, 小鼠 ELISA, ChIP, FACS 宿主: 山羊 Polyclonal unconjugated
anti-PR Domain Containing 16 (PRDM16) (AA 779-996) antibodyPRDM16 适用: 人 WB 宿主: 小鼠 Monoclonal 1740CT793-52-44 unconjugated
anti-PR Domain Containing 16 (PRDM16) (AA 539-588) antibodyPRDM16 适用: 人, 小鼠, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 16 (PRDM16) antibodyPRDM16 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 16 (PRDM16) (C-Term) antibodyPRDM16 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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PRDM16 antibody can be used for detection of PRDM16 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PRDM16 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- PRDM16 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- PRDM16 (PR Domain Containing 16 (PRDM16))
- 别名
- PRDM16 (PRDM16 产品)
- 别名
- PRDM16 antibody, wu:fc09g08 antibody, MEL1 antibody, PFM13 antibody, 5730557K01Rik antibody, C130091E20 antibody, csp1 antibody, mKIAA1675 antibody, mel1 antibody, PR/SET domain 16 antibody, PR domain containing 16 antibody, PRDM16 antibody, prdm16 antibody, Prdm16 antibody
- 背景
- PRDM16 Antibody: PRDM16 is a zinc finger transcription factor and contains an N-terminal PR domain. The reciprocal translocation t(1,3)(p36,q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36, q21)-positive MDS/AML. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Recent studies have shown that PRDM16 normally acts as a Smad3 binding protein that may be important for the development of orofacial structures through modulation of the TGF-beta signaling pathway. Other experiments have indicated that PRDM16 controls a bidirectional cell fate switch between skeletal myoblasts and brown fat cells.
- 分子量
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Predicted: 109, 120, 140 kDa
Observed: 140 kDa - 基因ID
- 63976
- UniProt
- Q9HAZ2
- 途径
- Stem Cell Maintenance, Brown Fat Cell Differentiation
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