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PICALM 抗体 (N-Term)

This anti-PICALM antibody is a 兔 多克隆 antibody detecting PICALM in WB, ELISA 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991249
发货至: 中国

Quick Overview for PICALM 抗体 (N-Term) (ABIN6991249)

抗原

See all PICALM 抗体
PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This PICALM antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)
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    N-Term

    纯化方法

    PICALM Antibody is affinity chromatography purified via peptide column.

    免疫原

    PICALM antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human PICALM. The immunogen is located within the first 50 amino acids of PICALM.

    亚型

    IgG
  • 应用备注

    PICALM antibody can be used for detection of PICALM by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PICALM Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    PICALM antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))

    别名

    PICALM

    背景

    PICALM Antibody: PICALM, also known as the clathrin assembly lymphoid myeloid leukemia (CALM) protein, co-localizes with clathrin at clathrin-coated areas of the plasma membrane and in the Golgi area, and is thought to be an important component of the coated pit internalization machinery. Fusion proteins involving PICALM have been implicated in acute myeloid and T-cell acute lymphoblastic leukemia. PICALM is also expressed in neurons and is present at the synapse where it facilitates the endocytosis of the synaptic vesicle protein VAMP2. Recent studies have identified variants of PICALM associated with Alzheimer's disease and have suggested this protein may play a role in the endocytosis and recycling of the amyloid protein precursor (APP).

    基因ID

    8301

    NCBI登录号

    NP_009097

    UniProt

    Q13492

    途径

    Synaptic Membrane
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