RWDD3 抗体 (C-Term)
This anti-RWDD3 antibody is a 兔 多克隆 antibody detecting RWDD3 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for RWDD3 抗体 (C-Term) (ABIN6991193)
抗原
See all RWDD3 抗体
RWDD3
(RWD Domain Containing 3 (RWDD3))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This RWDD3 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA
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抗原表位
- C-Term
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纯化方法
- RWDD3 Antibody is affinity chromatography purified via peptide column.
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免疫原
- RWDD3 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human RWDD3. The immunogen is located within the last 50 amino acids of RWDD3.
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亚型
- IgG
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anti-RWD Domain Containing 3 (RWDD3) (C-Term) antibody
RWDD3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RWD Domain Containing 3 (RWDD3) (N-Term) antibodyRWDD3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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RWDD3 antibody can be used for detection of RWDD3 by Western blot at 1 μ,g/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- RWDD3 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- RWDD3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- RWDD3 (RWD Domain Containing 3 (RWDD3))
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别名
- RWDD3
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背景
- RWDD3 Antibody: RWDD3 (RSUME), a small RWD-containing protein, has a central role in sumoylation by enhancing SUMO conjugation in the regulatory network of immune-inflammatory signals. RWDD3 increases Iκ,Beta sumoylation and stability. In addition, RWDD3 inhibits TNF-α,-induced kappaB-LUC (Luciferase) reporter activity, showing the functional consequence of Iκ,Beta increased stability. RSUME-enhanced sumoylation of Iκ,Beta leads to the inhibition of NF-κ,Beta activity on two well-known inflammatory genes, IL-8 and cyclooxygenase-2 (Cox-2) and therefore may also favor anti-inflammatory pathways. Expression of RWDD3 was induced under hypoxic conditions and it has a potential role during vascularization. Both BMP-4 and RWDD3 may be interesting targets for inhibiting steps involved in pituitary tumorigenesis.
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基因ID
- 25950
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NCBI登录号
- NP_056300
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UniProt
- Q9Y3V2
抗原
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