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TBKBP1 抗体 (C-Term)

This anti-TBKBP1 antibody is a 兔 多克隆 antibody detecting TBKBP1 in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991189
发货至: 中国

Quick Overview for TBKBP1 抗体 (C-Term) (ABIN6991189)

抗原

See all TBKBP1 抗体
TBKBP1 (TBK1 Binding Protein 1 (TBKBP1))

适用

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人, 小鼠, 大鼠

宿主

  • 28

克隆类型

  • 28
多克隆

标记

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This TBKBP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 500-550, C-Term

    纯化方法

    Prosapip2 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Prosapip2 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human Prosapip2. The immunogen is located within amino acids 500 - 550 of Prosapip2.

    亚型

    IgG
  • 应用备注

    Prosapip2 antibody can be used for detection of Prosapip2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Prosapip2 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    Prosapip2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    TBKBP1 (TBK1 Binding Protein 1 (TBKBP1))

    别名

    Prosapip2

    背景

    Prosapip2 Antibody: Prosapip2 (TBKBP1) is essential for signal transduction during viral infection thus plays a major role in the TNF/NF-κ,B pathway. It is an adaptor protein that constitutively binds TBK1 (TANK-binding kinase) and IKBKE and may play a role in antiviral innate immunity. Prosapip2 is a 615 amino acid adaptor protein belonging to the fibrillar collagen family, consisting of trimers of identical alpha 1 chains which are linked to each other by interchain disulfide bonds. It has a ubiquitous expression with highest levels in ovary, followed by the neuronal system. Prosapip2 binds to TBK1 and helps in the activation of IRF3 which controls the expression of antiviral genes during infection. Recent studies show that Prosapip2 is an interaction partner of ProSAP2/Shank3 and actin, suggesting a role as a linker molecule between postsynaptic density and the cytoskeleton.

    基因ID

    9755

    NCBI登录号

    NP_055541

    UniProt

    A7MCY6

    途径

    SARS-CoV-2 Protein Interactome
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