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TBKBP1 抗体 (C-Term)

TBKBP1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500543
发货至: 中国
  • 抗原 See all TBKBP1 抗体
    TBKBP1 (TBK1 Binding Protein 1 (TBKBP1))
    抗原表位
    • 13
    • 8
    • 8
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    • 26
    • 25
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 38
    克隆类型
    • 38
    多克隆
    标记
    • 15
    • 5
    • 5
    • 5
    • 4
    • 4
    This TBKBP1 antibody is un-conjugated
    应用范围
    • 34
    • 27
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects Prosapip2.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Peptide affinity chromatography
    免疫原
    Prosapip2 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human Prosapip2.
    亚型
    IgG
    Top Product
    Discover our top product TBKBP1 Primary Antibody
  • 应用备注
    ELISA. Western blot. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    TBKBP1 (TBK1 Binding Protein 1 (TBKBP1))
    别名
    TBKBP1 (TBKBP1 产品)
    别名
    TBKBP1 antibody, ProSAPiP2 antibody, SINTBAD antibody, 3110043L15Rik antibody, Prosapip2 antibody, TBK1 binding protein 1 antibody, TBKBP1 antibody, Tbkbp1 antibody
    背景
    Prosapip2 (TBKBP1) is essential for signal transduction during viral infection thus plays a major role in the TNF/NF-kappaB pathway. It is an adaptor protein that constitutively binds TBK1 (TANK-binding kinase) and IKBKE and may play a role in antiviral innate immunity. Prosapip2 is a 615 amino acid adaptor protein belonging to the fibrillar collagen family, consisting of trimers of identical alpha 1 chains which are linked to each other by interchain disulfide bonds. It has a ubiquitous expression with highest levels in ovary, followed by the neuronal system. Prosapip2 binds to TBK1 and helps in the activation of IRF3 which controls the expression of antiviral genes during infection. Recent studies show that Prosapip2 is an interaction partner of ProSAP2/Shank3 and actin, suggesting a role as a linker molecule between postsynaptic density and the cytoskeleton.Synonyms: KIAA0775, ProSAPiP2, Sintbad, TANK-binding kinase 1-binding protein 1, TBK1-binding protein 1
    基因ID
    9755
    NCBI登录号
    NP_055541
    UniProt
    A7MCY6
    途径
    SARS-CoV-2 Protein Interactome
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