ProSAPiP1 抗体 (C-Term)
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北京 101111
Quick Overview for ProSAPiP1 抗体 (C-Term) (ABIN6991188)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 590-640, C-Term
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纯化方法
- Prosapip1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Prosapip1 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human Prosapip1. The immunogen is located within amino acids 590 - 640 of Prosapip1.
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亚型
- IgG
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应用备注
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Prosapip1 antibody can be used for detection of Prosapip1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Prosapip1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Prosapip1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ProSAPiP1 (PROSAPIP1) (ProSAP-Interacting Protein 1 (PROSAPIP1))
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别名
- Prosapip1
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背景
- Prosapip1 Antibody: Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through ProSAP2/Shank3's PDZ domain and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed 'Fezzins'. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells.
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基因ID
- 9762
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NCBI登录号
- NP_055546
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UniProt
- O60299
抗原
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