JMJD1C 抗体 (N-Term)
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Quick Overview for JMJD1C 抗体 (N-Term) (ABIN6991178)
抗原
See all JMJD1C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 380-430, N-Term
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特异性
- This antibody will not cross-react with JMJD1A or JMJD1B.
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纯化方法
- JMJD1C Antibody is affinity chromatography purified via peptide column.
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免疫原
- JMJD1C antibody was raised against a 20 amino acid synthetic peptide from near the amino terminus of human JMJD1C. The immunogen is located within amino acids 380 - 430 of JMJD1C.
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亚型
- IgG
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anti-Jumonji Domain Containing 1C (JMJD1C) (AA 2-99) antibody
JMJD1C 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 5F12 unconjugated
anti-Jumonji Domain Containing 1C (JMJD1C) (AA 539-648) antibodyJMJD1C 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 1C (JMJD1C) (AA 2-99) antibodyJMJD1C 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3A8 unconjugated
anti-Jumonji Domain Containing 1C (JMJD1C) (AA 2019-2051) antibodyJMJD1C 适用: 人 WB 宿主: 兔 Polyclonal RB55072 unconjugated
anti-Jumonji Domain Containing 1C (JMJD1C) (N-Term) antibodyJMJD1C 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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JMJD1C antibody can be used for detection of JMJD1C by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- JMJD1C Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- JMJD1C antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- JMJD1C (Jumonji Domain Containing 1C (JMJD1C))
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别名
- JMJD1C
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背景
- JMJD1C Antibody: The jumonji domain containing 1C protein (JMJD1C) was initially discovered in silico, and later suggested to be a candidate gene for autism. Like the related proteins JMJD1A and JMJD1B, JMJD1C is a histone H3K9 demethylase implicated in the nuclear hormone receptor-based transcriptional regulation. JMJD1C mRNA is highly expressed in undifferentiated embryonic stem (ES) cells as well as pancreatic islet, diffuse-type gastric cancer, and other tissues and tumors. The JMJD1C gene promoter contain bHLH-, AP-1-, and POU5F1-binding sites, and as preferential expression of POU5F1 has been reported in ES cells, pancreatic islet, and diffuse-type gastric cancer, it has been suggested that POU5F1-mediated expression of JMJD1C reactivates previously silenced genes in ES cells and diffuse-type gastric cancer. At least three isoforms of JMJD1C are known to exist.
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基因ID
- 221037
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NCBI登录号
- NP_116165
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UniProt
- Q15652
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途径
- Nuclear Hormone Receptor Binding
抗原
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