JMJD1C 抗体 (N-Term)
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- 抗原 See all JMJD1C 抗体
- JMJD1C (Jumonji Domain Containing 1C (JMJD1C))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This JMJD1C antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects JMJD1C / TRIP8. It will not cross-react with JMJD1A or JMJD1B.
- 交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Peptide affinity chromatography
- 免疫原
- JMJD1C antibody was raised against a 20 amino acid peptide from near the amino terminus of human JMJD1C.
- 亚型
- IgG
- Top Product
- Discover our top product JMJD1C Primary Antibody
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anti-Jumonji Domain Containing 1C (JMJD1C) (AA 2-99) antibody
JMJD1C 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 5F12 unconjugated
anti-Jumonji Domain Containing 1C (JMJD1C) (AA 539-648) antibodyJMJD1C 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 1C (JMJD1C) (AA 2-99) antibodyJMJD1C 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3A8 unconjugated
anti-Jumonji Domain Containing 1C (JMJD1C) (AA 2019-2051) antibodyJMJD1C 适用: 人 WB 宿主: 兔 Polyclonal RB55072 unconjugated
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- 应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- JMJD1C (Jumonji Domain Containing 1C (JMJD1C))
- 别名
- JMJD1C / TRIP8 (JMJD1C 产品)
- 别名
- RP11-10C13.2 antibody, TRIP8 antibody, 5430433L24Rik antibody, D630035I23Rik antibody, Jmjdic antibody, Pr2 antibody, JMJD1C antibody, DKFZp469A034 antibody, jumonji domain containing 1C antibody, JMJD1C antibody, Jmjd1c antibody, jmjd1c antibody
- 背景
- The jumonji domain containing 1C protein (JMJD1C) was initially discovered in silico, and later suggested to be a candidate gene for autism. Like the related proteins JMJD1A and JMJD1B, JMJD1C is a histone H3K9 demethylase implicated in the nuclear hormone receptor-based transcriptional regulation. JMJD1C mRNA is highly expressed in undifferentiated embryonic stem (ES) cells as well as pancreatic islet, diffuse-type gastric cancer, and other tissues and tumors. The JMJD1C gene promoter contain bHLH-, AP-1-, and POU5F1-binding sites, and as preferential expression of POU5F1 has been reported in ES cells, pancreatic islet, and diffuse-type gastric cancer, it has been suggested that POU5F1-mediated expression of JMJD1C reactivates previously silenced genes in ES cells and diffuse-type gastric cancer. At least three isoforms of JMJD1C are known to exist.Synonyms: JHDM2C, Jumonji domain-containing protein 1C, KIAA1380, Probable JmjC domain-containing histone demethylation protein 2C, Thyroid receptor-interacting protein 8
- 基因ID
- 221037
- NCBI登录号
- NP_116165
- UniProt
- Q15652
- 途径
- Nuclear Hormone Receptor Binding
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