EPH Receptor A10 抗体 (N-Term)
Quick Overview for EPH Receptor A10 抗体 (N-Term) (ABIN6991150)
抗原
See all EPH Receptor A10 (EPHA10) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 120-170, N-Term
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纯化方法
- EphA10 Antibody is affinity chromatography purified via peptide column.
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免疫原
- EphA10 antibody was raised against a 14 amino acid synthetic peptide of near the amino terminus of human EphA10. The immunogen is located within amino acids 120 - 170 of EphA10.
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亚型
- IgG
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应用备注
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EphA10 antibody can be used for detection of EphA10 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- EphA10 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- EphA10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- EPH Receptor A10 (EPHA10)
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别名
- EphA10
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背景
- EphA10 Antibody: Eph receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility of neuronal and endothelial cells in central nervous system function and in development. Eph receptors can be divided into two subgroups: EphA and EphB. In mammals, the EphA class consists of eight members (EphA 1-7 and 10) that in general bind to ephrin-A members linked to the cell membrane through a glycosylphosphatidylinositol linkage. The EphB class consists of six members (EphB 1-6) that in general bind ephrin-B members that transverse the cell membrane. The Ephrin / EPH signaling pathway networks with the WNT signaling pathway during embryogenesis, tissue regeneration, and carcinogenesis. Recent studies show that Eph/EFN might be relevant in normal B-cell biology and could represent new potential prognostic markers and therapeutic targets for CLL.
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基因ID
- 284656
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NCBI登录号
- NP_001092909
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UniProt
- Q5JZY3
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途径
- RTK signaling
抗原
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