HAAO 抗体 (N-Term)
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北京 101111
Quick Overview for HAAO 抗体 (N-Term) (ABIN6991149)
抗原
See all HAAO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-80, N-Term
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纯化方法
- HAAO Antibody is affinity chromatography purified via peptide column.
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免疫原
- HAAO antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human HAAO. The immunogen is located within amino acids 30 - 80 of HAAO.
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亚型
- IgG
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anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 153-223) antibody
HAAO 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 97-196) antibodyHAAO 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D1 unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) antibodyHAAO 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 101-200) antibodyHAAO 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 72-121) antibodyHAAO 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (N-Term) antibodyHAAO 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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HAAO antibody can be used for detection of HAAO by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- HAAO Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- HAAO antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
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别名
- HAAO
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背景
- HAAO Antibody: HAAO (3-Hydroxyanthranilate 3, 4-dioxygenase) is a monomeric cytosolic protein of the family of intramolecular dioxygenases containing non-heme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is present in low amounts in the central nervous system. This enzyme participates in tryptophan metabolism. It employs one cofactor, iron. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurological and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. Furthermore, recent study shows that HAAO are excellent candidate biomarkers for detecting ovarian cancer.
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基因ID
- 23498
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NCBI登录号
- NP_036337
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UniProt
- P46952
抗原
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