MC4R 抗体 (N-Term)
Quick Overview for MC4R 抗体 (N-Term) (ABIN6991129)
抗原
See all MC4R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- MC4R Antibody is affinity chromatography purified via peptide column.
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免疫原
- MC4R antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human MC4R. The immunogen is located within the first 50 amino acids of MC4R.
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亚型
- IgG
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anti-Melanocortin 4 Receptor (MC4R) (AA 1-50) antibody
MC4R 适用: 人, 大鼠, 小鼠 ELISA, IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (N-Term) antibodyMC4R 适用: 人, 猴, 马 IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (AA 6-20), (Extracellular) antibodyMC4R 适用: 人 WB, IHC, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (AA 25-57) antibodyMC4R 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB52063 unconjugated
anti-Melanocortin 4 Receptor (MC4R) (AA 21-33) antibodyMC4R 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (Cytoplasmic Domain) antibodyMC4R 适用: 人, 绵羊, 兔, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (C-Term) antibodyMC4R 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (C-Term) antibodyMC4R 适用: 人, 大鼠, 小鼠, 绵羊, 兔, Cow, 猴, 犬, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (AA 1-50) antibody (AbBy Fluor® 488)MC4R 适用: 人, 大鼠, 小鼠 IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 488
anti-Melanocortin 4 Receptor (MC4R) (N-Term) antibodyRecent MC4R 适用: 人 ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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MC4R antibody can be used for detection of MC4R by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- MC4R Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- MC4R antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- MC4R (Melanocortin 4 Receptor (MC4R))
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别名
- MC4R
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背景
- MC4R Antibody: The melanocortin-4 receptor (MC4R) is a member of the superfamily of seven transmembrane G-protein coupled receptors that are involved in multiple signal transduction pathways including the cAMP and MAPK signaling pathways. It is thought that the melanocortin system modulates energy expenditure and insulin sensitivity, activation of the MC4R results in the inhibition of c-Jun N-terminal kinase (JNK) activity and promotes insulin signaling. MC4R-null mice display maturity onset obesity characterized by hyperphagia, increased adiposity, hyperinsulinaemia and hyperleptinaemia, suggesting that like other obesity-linked genes such as FTO, PTER, and NPC1, MC4R is a potential candidate target for the treatment of obesity.
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基因ID
- 4160
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NCBI登录号
- NP_005903
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UniProt
- P32245
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途径
- Hormone Transport, cAMP Metabolic Process, Feeding Behaviour
抗原
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