RSPO1 抗体 (N-Term)
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- 抗原 See all RSPO1 抗体
- RSPO1 (R-Spondin 1 (RSPO1))
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抗原表位
- N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RSPO1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 特异性
- At least three isoforms of RSPO1 are known to exist, this antibody will detect the largest and smallest isoforms. RSPO1 antibody will not cross-react with other RSPO family members.
- 纯化方法
- RSPO1 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- Anti-RSPO1 antibody was raised against a peptide corresponding to 16 amino acids near the amino terminus of human RSPO1. The immunogen is located within the first 50 amino acids of RSPO1.
- 亚型
- IgG
- Top Product
- Discover our top product RSPO1 Primary Antibody
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anti-R-Spondin 1 (RSPO1) (AA 21-135) antibody
RSPO1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (AA 21-135) antibodyRSPO1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (AA 136-262) antibodyRSPO1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (AA 21-263) antibodyRSPO1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (N-Term) antibodyRSPO1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (AA 21-263) antibodyRSPO1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) antibodyRSPO1 适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (N-Term) antibodyRSPO1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) antibodyRSPO1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7A6 unconjugated
anti-R-Spondin 1 (RSPO1) antibodyRSPO1 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: 0.5-2 μ,g/mL, IHC: 2.5-5 μ,g/mL, IF: 5 μ,g/mL.
Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry in human samples, Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- RSPO1 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- RSPO1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- RSPO1 (R-Spondin 1 (RSPO1))
- 别名
- RSPO1 (RSPO1 产品)
- 别名
- RGD1565558 antibody, CRISTIN3 antibody, RSPO antibody, R-spondin antibody, Rspondin antibody, wu:fj81e05 antibody, zgc:92153 antibody, R-spondin 1 antibody, Rspo1 antibody, RSPO1 antibody, LOC100049655 antibody, rspo1 antibody
- 背景
- RSPO1 Antibody: RSPO1 is a member of a family of secreted growth factors that can operate through the canonical Wnt signaling pathway by stabilizing the intracellular beta-catenin, thereby regulating functions mediated by beta-catenin such as cell fate decisions and embryonic patterning. RSPO1 was recently identified through linkage analysis to be involved in sex determination and mammalian ovarian development. RSPO1 is thought to regulate cellular responsiveness to Wnt ligands by modulating the cell-surface expression of the Wnt co-receptor LRP6 by interfering with the DKK/Kremen-mediated internalization of LRP6 through an interaction with Kremen, resulting in increased LRP6 cell-surface levels.
- 分子量
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Predicted: 29kD
Observed: 36 kD (Post-modification: 1 N-linked glycosylation) kDa - 基因ID
- 284654
- NCBI登录号
- NP_001033722
- UniProt
- Q2MKA7
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