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RSPO1 抗体 (AA 21-263)

RSPO1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7166935
发货至: 中国
  • 抗原 See all RSPO1 抗体
    RSPO1 (R-Spondin 1 (RSPO1))
    抗原表位
    • 15
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 21-263
    适用
    • 45
    • 40
    • 35
    • 15
    • 15
    • 15
    • 15
    • 15
    宿主
    • 48
    • 6
    • 1
    克隆类型
    • 49
    • 6
    多克隆
    标记
    • 24
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This RSPO1 antibody is un-conjugated
    应用范围
    • 38
    • 15
    • 13
    • 11
    • 11
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human R-spondin-1 protein (21-263AA)
    亚型
    IgG
    Top Product
    Discover our top product RSPO1 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    RSPO1 (R-Spondin 1 (RSPO1))
    别名
    RSPO1 (RSPO1 产品)
    别名
    RGD1565558 antibody, CRISTIN3 antibody, RSPO antibody, R-spondin antibody, Rspondin antibody, wu:fj81e05 antibody, zgc:92153 antibody, R-spondin 1 antibody, Rspo1 antibody, RSPO1 antibody, LOC100049655 antibody, rspo1 antibody
    背景

    Background: Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Has a essential roles in ovary determination.

    Aliases: CRISTIN3, FLJ40906, hRspo1, R spondin homolog, R spondin homolog (Xenopus laevis), R spondin1, R-spondin-1, Roof plate specific spondin, Roof plate-specific spondin-1, RP11-566C13.1, RSPO, Rspo1, RSPO1_HUMAN

    UniProt
    Q2MKA7
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