SH3BP4 抗体 (C-Term)
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北京 101111
Quick Overview for SH3BP4 抗体 (C-Term) (ABIN6991118)
抗原
See all SH3BP4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 860-910, C-Term
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纯化方法
- SH3BP4 Antibody is affinity chromatography purified via peptide column.
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免疫原
- SH3BP4 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human SH3BP4. The immunogen is located within amino acids 860 - 910 of SH3BP4.
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亚型
- IgG
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应用备注
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SH3BP4 antibody can be used for detection of SH3BP4 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in rat samples and Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- SH3BP4 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- SH3BP4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))
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别名
- SH3BP4
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背景
- SH3BP4 Antibody: SH3BP4 was initially isolated as a novel cDNA using differential display analysis using cultured human corneal fibroblasts. The protein contains three Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. SH3BP4 has been shown to interact with specific endocytic proteins such as clathrin, dynamin, and the transferrin receptor (TfR) and localizes to TfR-containing coated pits and vesicles. It is thought to be involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of TfR. At least two isoforms of SH3BP4 are known to exist.
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基因ID
- 23677
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NCBI登录号
- NP_055336
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UniProt
- Q9P0V3
抗原
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