KIT Ligand 抗体 (AA 100-150)
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北京 101111
Quick Overview for KIT Ligand 抗体 (AA 100-150) (ABIN6991117)
抗原
See all KIT Ligand (KITLG) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-150
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纯化方法
- SCF Antibody is affinity chromatography purified via peptide column.
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免疫原
- Anti-SCF antibody was raised against a peptide corresponding to 18 amino acids near the center of human SCF. The immunogen is located within amino acids 100-150 of SCF.
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亚型
- IgG
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anti-KIT Ligand (KITLG) (AA 151-250) antibody
KITLG 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) antibodyKITLG 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) antibodyKITLG 适用: 人 WB, IHC, ELISA, IHC (p), Neut 宿主: 山羊 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (AA 26-190) antibodyKITLG 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (AA 244-273) antibodyKITLG 适用: 人 WB, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (Middle Region) antibodyKITLG 适用: 人, 小鼠, 大鼠, Pig, 犬, Cow, 山羊, 马, 兔, 绵羊, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (AA 180-229) antibodyKITLG 适用: 人, 小鼠, 大鼠, Pig, 犬, Cow, 山羊, 马, 兔, 绵羊, 小鸡, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) antibodyKITLG 适用: 人, 小鼠, 大鼠 WB, IHC (p), ELISA (Capture) 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (AA 26-214) antibodyKITLG 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (AA 201-234), (C-Term) antibodyKITLG 适用: 人 WB 宿主: 兔 Polyclonal RB50736 unconjugated
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应用备注
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WB: 1-2 μ,g/mL, IHC: 2.5 μ,g/mL, IF: 20 μ,g/mL.
Antibody validated: Western Blot in human, mouse and rat samples, Immunohistochemistry in mouse samples, Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- SCF Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- SCF antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- KIT Ligand (KITLG)
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别名
- SCF
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背景
- SCF Antibody: Stem cell factor (SCF) is the ligand of the c-Kit oncogene and is expressed by various structural and inflammatory cells in the airways. Binding of SCF by the c-Kit receptor leads to homodimerization of the receptor and the activation of signalling pathways such as PI-3, PLC-gamma, Jak/STAT, and MAP kinase pathways. SCF expression leads to the induction of mast cell survival and the expression and release of histamine, pro-inflammatory cytokines and chemokines. The inhibition of the SCF/c-Kit pathway leads to a decrease in histamine levels, mast cell and eosinophil infiltration, IL-4 production and airway hyperresponsiveness, suggesting this pathway may be a useful therapeutic target in inflammatory diseases such as asthma. At least two isoforms of SCF are known to exist.
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分子量
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Predicted: 31kD
Observed: 36 kD (31kD + 4 N-linked Glycosylations) kDa -
基因ID
- 4254
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UniProt
- P21583
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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