TNFAIP3 抗体 (C-Term)
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北京 101111
Quick Overview for TNFAIP3 抗体 (C-Term) (ABIN6991101)
抗原
See all TNFAIP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- TNFAIP3 Antibody is affinity chromatography purified via peptide column.
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免疫原
- TNFAIP3 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human TNFAIP3. The immunogen is located within the last 50 amino acids of TNFAIP3.
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亚型
- IgG
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anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (AA 1-190) antibody
TNFAIP3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (Internal Region) antibodyTNFAIP3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (AA 51-150) antibodyTNFAIP3 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (AA 1-300) antibodyTNFAIP3 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (AA 97-183) antibodyTNFAIP3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) antibodyTNFAIP3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (C-Term) antibodyTNFAIP3 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) antibodyTNFAIP3 适用: 人 WB, IP 宿主: 小鼠 Monoclonal 59A426 unconjugated
anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) (AA 321-370) antibodyTNFAIP3 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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TNFAIP3 antibody can be used for detection of TNFAIP3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TNFAIP3 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TNFAIP3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TNFAIP3 (Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3))
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别名
- TNFAIP3
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背景
- TNFAIP3 Antibody: TNFAIP3, also known as A20, is located in chromosome band 6q23, a region that is often deleted in B cell lymphomas. Recently, it was identified as a tumor suppressor gene in Hodgkin lymphoma and several subtypes of non-Hodgkin lymphomas. TNFAIP3 was initially identified as a zinc-finger protein that is rapidly and transiently induced by TNF-α, inhibiting NF-κ,B-dependent gene expression, and protecting cells from TNF-α,-cytotoxicity. Overexpression of TNFAIP3 also inhibits the TLR2- and TLR4-mediated interleukin-8 synthesis in airway epithelial cells, suggesting that TNFAIP3 also acts as a negative regulator of TLR-mediated inflammatory responses, thereby protecting the host against harmful over-responses to pathogens. At least two isoforms of TNFAIP3 are known to exist.
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基因ID
- 21929
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UniProt
- Q60769
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Production of Molecular Mediator of Immune Response
抗原
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