CDIP1 抗体 (AA 70-120)
Quick Overview for CDIP1 抗体 (AA 70-120) (ABIN6991072)
抗原
See all CDIP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 70-120
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纯化方法
- CDIP Antibody is affinity chromatography purified via peptide column.
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免疫原
- CDIP antibody was raised against a 19 amino acid synthetic peptide near the center of human CDIP. The immunogen is located within amino acids 70 - 120 of CDIP.
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亚型
- IgG
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anti-LITAF-Like Protein (CDIP1) (AA 1-208) antibody
CDIP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-LITAF-Like Protein (CDIP1) (AA 100-200) antibodyCDIP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-LITAF-Like Protein (CDIP1) (Middle Region 1) antibodyCDIP1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-LITAF-Like Protein (CDIP1) (Center) antibodyCDIP1 适用: 人, 小鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-LITAF-Like Protein (CDIP1) antibodyCDIP1 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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CDIP antibody can be used for detection of CDIP by Western blot at 0.25 - 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CDIP Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CDIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- CDIP1 (LITAF-Like Protein (CDIP1))
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别名
- CDIP
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背景
- CDIP Antibody: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death, loss of its functions contributes to the development of most cancers. CDIP is a novel pro-apoptotic target gene whose inhibition abrogates p53-mediated apoptotic responses. Overexpression of CDIP induced apoptosis in transfected cells while siRNA suppression of caspase-8 mRNA blocked this CDIP-induced apoptosis, indicating that the CDIP-dependent apoptosis pathway proceeds through extrinsic cell death pathway. CDIP may thus represent a novel target for drug design to maximize p53 response and sensitize tumor cells to cancer therapy. Multiple isoforms of CDIP are known to exist.
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基因ID
- 29965
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NCBI登录号
- NP_037531
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UniProt
- Q9H305
抗原
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