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CDIP1 抗体 (Center)

CDIP1 适用: 人, 小鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499607
发货至: 中国
  • 抗原 See all CDIP1 抗体
    CDIP1 (LITAF-Like Protein (CDIP1))
    抗原表位
    • 2
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 6
    • 4
    • 1
    人, 小鼠
    宿主
    • 5
    • 2
    克隆类型
    • 7
    多克隆
    标记
    • 7
    This CDIP1 antibody is un-conjugated
    应用范围
    • 7
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to CDIP.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    19 amino acid peptide near the center of Human CDIP
    亚型
    IgG
    Top Product
    Discover our top product CDIP1 Primary Antibody
  • 应用备注
    ELISA. Western Blot: CDIP antibody can be used for detection of CDIP at 0.25 - 0.5 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CDIP1 (LITAF-Like Protein (CDIP1))
    别名
    LITAF-Like Protein (CDIP1 产品)
    别名
    RGD1310686 antibody, MGC165666 antibody, MGC97537 antibody, 2700048O17Rik antibody, 5730403B10Rik antibody, AU018521 antibody, AW742692 antibody, CDIP antibody, C16orf5 antibody, I1 antibody, LITAFL antibody, MGC52765 antibody, MGC127651 antibody, cell death-inducing p53 target 1 antibody, LITAF-like protein antibody, cell death inducing Trp53 target 1 antibody, cell death inducing p53 target 1 antibody, cell death-inducing p53 target 1 L homeolog antibody, Cdip1 antibody, cdip1 antibody, Bm1_00175 antibody, LOC100168843 antibody, CDIP1 antibody, cdip1.L antibody
    背景
    The p53 tumor-suppressor gene integrates numerous signals that control cell life and death, loss of its functions contributes to the development of most cancers. CDIP is a novel pro-apoptotic target gene whose inhibition abrogates p53-mediated apoptotic responses. Overexpression of CDIP induced apoptosis in transfected cells while siRNA suppression of caspase-8 mRNA blocked this CDIP-induced apoptosis, indicating that the CDIP-dependent apoptosis pathway proceeds through extrinsic cell death pathway. CDIP may thus represent a novel target for drug design to maximize p53 response and sensitize tumor cells to cancer therapy. Multiple isoforms of CDIP are known to exist.Synonyms: C16orf5, CDIP, Cell death-inducing protein, Transmembrane protein I1
    基因ID
    29965
    NCBI登录号
    NP_037531
    UniProt
    Q9H305
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