TTBK2 抗体 (C-Term)
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北京 101111
Quick Overview for TTBK2 抗体 (C-Term) (ABIN6991063)
抗原
See all TTBK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- TTBK2 antibody is human specific. At least four isoforms of TTBK2 are known to exist, this antibody will detect only the two largest isoforms.
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纯化方法
- TTBK2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- TTBK2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human TTBK2. The immunogen is located within the last 50 amino acids of TTBK2.
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亚型
- IgG
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anti-tau Tubulin Kinase 2 (TTBK2) (AA 1185-1244) antibody
TTBK2 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-tau Tubulin Kinase 2 (TTBK2) (AA 1185-1244) antibodyTTBK2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-tau Tubulin Kinase 2 (TTBK2) antibodyTTBK2 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-tau Tubulin Kinase 2 (TTBK2) (AA 1-478) antibodyTTBK2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-tau Tubulin Kinase 2 (TTBK2) (AA 217-245), (N-Term) antibodyTTBK2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB31984 unconjugated
anti-tau Tubulin Kinase 2 (TTBK2) (C-Term) antibodyTTBK2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-tau Tubulin Kinase 2 (TTBK2) (AA 270-319) antibodyTTBK2 适用: 人, 小鼠, 大鼠, 犬, 马, Pig, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-tau Tubulin Kinase 2 (TTBK2) (N-Term) antibodyTTBK2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-tau Tubulin Kinase 2 (TTBK2) (AA 21-314) antibodyTTBK2 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-tau Tubulin Kinase 2 (TTBK2) (AA 224-253), (N-Term) antibodyTTBK2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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TTBK2 antibody can be used for detection of TTBK2 by immunohistochemistry at 5 μ,g/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TTBK2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TTBK2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TTBK2 (tau Tubulin Kinase 2 (TTBK2))
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别名
- TTBK2
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背景
- TTBK2 Antibody: Tau tubulin kinase (TTBK2) is a serine/threonine kinase whose substrates are thought to include the tau and tubulin proteins. Mutations in the TTBK2 gene cause spinocerebellar ataxia type 11 (SCA11), a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem. Recent studies have shown that increased levels of TTBK2 expression in kidney carcinoma and melanoma cell lines increases resistance to the chemotherapeutic agent Sunitinib, and that reduction of TTBK2 though the use of siRNA sensitized these cell lines to the effects of Sunitib, suggesting that TTBK2 can be used as a resistance marker as well a potential target to overcome resistance.
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基因ID
- 146057
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UniProt
- Q6IQ55
抗原
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