GLE1 抗体 (AA 390-440)
Quick Overview for GLE1 抗体 (AA 390-440) (ABIN6991041)
抗原
See all GLE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 390-440
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纯化方法
- Gle1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Gle1 antibody was raised against a 14 amino acid synthetic peptide near the center of human Gle1. The immunogen is located within amino acids 390 - 440 of Gle1.
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亚型
- IgG
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anti-GLE1 RNA Export Mediator (GLE1) (AA 141-380) antibody
GLE1 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-GLE1 RNA Export Mediator (GLE1) (AA 140-240) antibodyGLE1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-GLE1 RNA Export Mediator (GLE1) (AA 1-698) antibodyGLE1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-GLE1 RNA Export Mediator (GLE1) (AA 611-698) antibodyGLE1 适用: 大鼠 ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-GLE1 RNA Export Mediator (GLE1) (AA 218-267) antibodyGLE1 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-GLE1 RNA Export Mediator (GLE1) (AA 1-300) antibodyGLE1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-GLE1 RNA Export Mediator (GLE1) (C-Term) antibodyGLE1 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Gle1 antibody can be used for detection of Gle1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Gle1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Gle1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- GLE1 (GLE1 RNA Export Mediator (GLE1))
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别名
- Gle1
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背景
- Gle1 Antibody: The proper expression of gene products in eukaryotic cells relies on efficient transport of mRNA molecules out of the nucleus. Gle1 is an essential mRNA export factor in both human and yeast cells. It associates with the nuclear pore complex (NPC) through hCG1 and NUP155 in mammalian cells and in conjunction with inositol hexakisphosphate (IP6), stimulates Dbp5, a member of the DEAD-box helicase family, triggering mRNP remodeling and facilitating RNA export from the nucleus. Recent evidence suggests that mutations in Gle1 causing defects in mRNA export can result in human disease. At least three isoforms of Gle1 are known to exist.
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基因ID
- 2733
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NCBI登录号
- NP_001003722
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UniProt
- Q53GS7
抗原
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