DISP2 抗体 (C-Term)
This anti-DISP2 antibody is a 兔 多克隆 antibody detecting DISP2 in ELISA 和 WB. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for DISP2 抗体 (C-Term) (ABIN6991010)
抗原
See all DISP2 抗体
DISP2
(Dispatched Homolog 2 (DISP2))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This DISP2 antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB)
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抗原表位
- AA 1210-1260, C-Term
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纯化方法
- Disp2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Disp2 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human Disp2. The immunogen is located within amino acids 1210 - 1260 of Disp2.
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亚型
- IgG
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anti-Dispatched Homolog 2 (DISP2) (AA 1101-1200) antibody
DISP2 适用: 人 IF (cc), IF (p), ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Disp2 antibody can be used for the detection of Disp2 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Disp2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Disp2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- DISP2 (Dispatched Homolog 2 (DISP2))
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别名
- Disp2
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背景
- Disp2 Antibody: Disp2 is the second of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing cells. Hedgehog is a major player in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis and the Disp proteins have been implicated in these pathways. Recently, it has been shown that Disp2 is translationally regulated by the microRNA miR-214 in zebrafish. Expression of this miRNA decreased Disp2 promoter activity in vitro and its overexpression in zebrafish resulted in a phenotype identical to that observed by Disp2 mutants. At least two isoforms of Disp2 are known to exist. This Disp2 antibody is predicted to not cross-react with Disp1 or Disp3.
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基因ID
- 85455
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UniProt
- A7MBM2
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途径
- Hedgehog Signaling
抗原
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