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STK39 抗体 (AA 360-410)

This anti-STK39 antibody is a 兔 多克隆 antibody detecting STK39 in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991004
发货至: 中国

Quick Overview for STK39 抗体 (AA 360-410) (ABIN6991004)

抗原

See all STK39 抗体
STK39 (serine threonine Kinase 39 (STK39))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This STK39 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 360-410

    纯化方法

    Stk39 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Stk39 antibody was raised against a 18 amino acid synthetic peptide from near the center of human Stk39. The immunogen is located within amino acids 360 - 410 of Stk39.

    亚型

    IgG
  • 应用备注

    Stk39 antibody can be used for detection of Stk39 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

    Antibody validated: Western Blot in rat samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Stk39 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    Stk39 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    STK39 (serine threonine Kinase 39 (STK39))

    别名

    Stk39

    背景

    Stk39 Antibody: The serine/threonine kinase Stk39 belongs to the STE20 family, a group of kinases that are known to interact with inflammation-related kinases (such as p38, JNK, NKCC1, PKC-theta, WNK and MLCK), and with transcription factor AP-1. The STE 20 family is involved in diverse biological phenomena, including cell differentiation, cell transformation/ proliferation, cytoskeleton rearrangement, and the regulation of ion transporters. STK39 contains an N-terminal series of proline and alanine repeats (PAPA box), followed by a serine/threonine kinase catalytic domain and is abundantly expressed in the brain. STK39 is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled co-transporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. Recent studies show that STK39 tend to be a novel candidate gene for autism and hypertension.

    基因ID

    27347

    NCBI登录号

    NP_037365

    UniProt

    Q9UEW8
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