IL-34 抗体 (N-Term)
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北京 101111
Quick Overview for IL-34 抗体 (N-Term) (ABIN6990969)
抗原
See all IL-34 (IL34) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-80, N-Term
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纯化方法
- IL-34 Antibody is affinity chromatography purified via peptide column.
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免疫原
- IL-34 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human IL-34. The immunogen is located within amino acids 30 - 80 of IL-34.
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亚型
- IgG
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应用备注
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IL-34 antibody can be used for the detection of IL-34 by Western blot at 0.25 μ,g/mL. Despite its predicted molecular weight, IL-34 will often run at higher molecular weight in SDS-PAGE.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- IL-34 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- IL-34 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- IL-34 (IL34) (Interleukin 34 (IL34))
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别名
- IL-34
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背景
- IL-34 Antibody: Interleukin-34 (IL-34) was identified through a functional screening of a library of secreted proteins after transfection of an embryonic kidney cell line with recombinant cDNAs. Flow cytometry and monocyte viability assays demonstrated increased survival and/or proliferation of monocytes induced by IL-34 and specific binding of IL-34 to CD14+ monocytes. IL-34 is a second ligand to the colony stimulating factor (CSF)-1 receptor in addition to CSF1. Like CSF1, IL-34 stimulates phosphorylation of ERK1 and ERK2 in human monocytes and induces differentiation of bone marrow cells into macrophages.
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分子量
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Predicted: 26 kDa
Observed: 42-48 kDa -
基因ID
- 146433
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UniProt
- Q6ZMJ4
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途径
- RTK signaling
抗原
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